For Radiologists

For Radiologists2019-05-31T19:58:09-05:00

The Vector Surgical Tissue Orientation System includes both MarginMarker sterile dye and CorrectClips radiographic markers.

Radiologists can more quickly and efficiently evaluate the intra-operative images to confirm that adequate margins of healthy tissue are present in the specimen.

The Problem

In cancer surgery, the single most important predictor of local recurrence is the tissue margins.1,2  Other methods used to label tissue margins on the specimen x-ray, such as metal tags, can cause error by obstructing the view of the lesion and creating shadows on the image. This may lead to error or delay.

The Solution

Vector Surgical’s Tissue Orientation System, consisting of the MarginMarker™ sterile ink kit and CorrectClips™ radiographic markers, provides secure and accurate designation of specimen margins, potentially resulting in more accurate re-excisions,3 fewer unnecessary re-excisions,3,4 lower cancer recurrence,1,5,6 and improved cosmesis.3

Clarity and Efficiency

Radiology receives images on which the specimen is fully visible and margins are labeled with CorrectClips to indicate the orientation. The tissue is displayed without obstruction or confounding elements that can otherwise cause error or delay.


Validity of Orientation on the Image
  • CorrectClips allow a complete view of tissue so that lesions are quickly located. The Clips are translucent on the image; only the letters indicating orientation show brightly. This is superior to metal tags, which block the view of tissue behind the tag, and which cast a “shadow” that also occludes visibility of the tissue on the image.
  • CorrectClips grip dense or fatty tissue securely and are compatible with compression. Each letter tag rotates and features two perpendicular faces on which the letter appears for optimal visibility on the image.
  • CorrectClips maintain orientation of the specimen over the recommended two orthogonal views.3,4,7,8
Validity of Microcalcifications on the Image
  • MarginMarker sterile inks are compatible with intraoperative imaging. Non-sterile inks can mimic microcalcifications, confounding the identification of actual microcalcifications on the image.9


Better Patient Outcomes
  • More accurate re-excisions3
  • Fewer unnecessary re-excisions3,4
  • Potentially lower cancer recurrence1,5,6
  • Improved cosmesis3
  • Less time lost to re-imaging due to an obstructed view of the lesion or ambiguous orientation.
  • Less possible confusion due to artifacts from non-sterile inks.
  • More efficient radiologist-surgeon communication.


  1. Gage, I.; Schnitt, S.J.; Nixon, A.J.; Silver, B.; Recht, A.; Troyan, S.L.; Eberlein, T.; Love, S.M.; Gelman, R.; Harris, J.R.; and Connolly, J.L. “Pathologic Margin Involvement and the Risk of Recurrence in Patients Treated with Breast-Conserving Therapy.” Cancer 78.9 (1996): 1921-1928.
  2. MacDonald, H.R.; Silverstein, M.J.; Mabry, H.; Moorthy, B.; Ye, W.; Epstein, M.S.; Holmes, D.; Silberman, H.; and Lagios, M. “Local Control in Ductal Carcinoma In Situ Treated by Excision Alone: Incremental Benefit of Larger Margins.” American Journal of Surgery 190.4 (2005): 521-525.
  3. Landercasper, J., Attai, D., Atisha, D., Beitsch, P., Bosserman, L., Boughey, J., Carter, J., Edge, S., Feldman, S., Froman, J. and Greenberg, C. “Toolbox to reduce lumpectomy reoperations and improve cosmetic outcome in breast cancer patients: The American Society of Breast Surgeons Consensus Conference.” Annals of Surgical Oncology 22.10 (2015): 3174-3183.
  4. Dooley, W.C. and Parker, J.  American Journal of Surgery 190 (2005): 606-608.
  5. Lovrics, P.J.; Cornacchi, S. D.; Farrokhyar, F.; Garnett, A.; Chen, V.; Franic, S.; and Simunovic, M.  The American Journal of Surgery (2009): 197, 740-746.
  6. Menes, T.S.; Tartter, P.I.; Bleiweiss, I.; Godbold, J.H.; Estabrook, A.; and Smith, S.R. “The Consequence of Multiple Re-excisions to Obtain Clear Lumpectomy Margins in Breast Cancer Patients.” Annals of Surgical Oncology 12.11 (2005): 881-885.
  7. Rebner, M; Pennes, D.R.; Baker, D.E.; Adler, D.D.; and Boyd, P. “Two-View Specimen Radiography in Surgical Biopsy of Nonpalpable Breast Masses.” American Journal of Roentgenology 149 (1987): 283-285.
  8. Britton, P.D.; Sonoda, L.I.; Yamamoto, A.K.; Koo, B.; Soh, E.; and Goud, A.  European Journal of Radiology 79 (2011): 245-249.
  9. Wong, J.W.; Bai, H.; Abdul-Karim, F.W.; and MacLennan, G.T. The Breast Journal10.5 (2004): 423-426.
Additional Medical References

Vector Surgical, the Vector Surgical Logo, MarginMarker, CorrectClips, and SilversteinWrap are trademarks of Vector Surgical, LLC. Reg. U.S. Pat & TM Off.